Why is CankerClear™ So Effective?

CankerClear™ is a breakthrough proprietary treatment that effectively combines the most powerful and extensively researched ingredients, giving you an all-in-one solution. Every single ingredient in CankerClear™ was hand-picked by a team of medical doctors and scientific researchers, based on clinical data and designed to treat canker sores and get results more effectively than any other canker sore treatment available.

CankerClear™ contains 7 tested ingredients that meet the strength and purity standards of the USP/NF (United States Pharmacopeia–National Formulary). Each ingredient was carefully researched and included based on clinical data. No other non-prescription solution comes close to CankerClear™ in terms of quality and purity of ingredients.

Recommended Directions: Apply a pinch of the powder on or near the inflammation or sore. Allow 60 to 100 seconds before removing powder. Your mouth will become wet with saliva. Use the saliva and powder mixture to swish thoroughly for up to three minutes. Repeat 2 - 3 times during the day. As a preventative, mix powder with water and swish in your mouth 1 - 2 times a week.

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CankerClear™ 's - Proprietary Blend of Ingredients:

Alum (Aluminum Potassium Sulfate) has many uses as an astringent and antiseptic in various industrial, cosmetic, chemical and cooking and baking processes. It is both an acid and an astringent which is to say, a compound that causes shrinking or constricting of blood vessels and/or mucous membranes. Alum Powder is often used for extracting the water out of food (e.g. pickle making). It is suggested that it may offer similar benefits for canker sores too, by removing the moisture from the ulcer which then gives it chance to heal. It has been shown to have antiperspirant and antibacterial properties which also play a part in absorbing water.

*References:
Aguilar, T. N.; Blaug, S.M.; Zopf, L.C. (July 1956). "A study of the antibacterial activity of some complex aluminum salts". Journal of the American Pharmaceutical Association. American Pharmaceutical Association 45 (7): 498–500.PMID 13345689.
Greenwood, N. N.; & Earnshaw, A. (1997). Chemistry of the Elements (2nd Edn.), Oxford: Butterworth-Heinemann. ISBN 0-7506-3365-4.
Kanlayavattanakul, M.; Lourith, N. (1 August 2011). "Body malodours and their topical treatment agents". International Journal of Cosmetic Science 33 (4): 298–311. doi:10.1111/j.1468-2494.2011.00649.x. PMID 21401651

Vitamin B12 is mostly known for its energy-enhancing properties and is especially important for the brain and nervous system, and its role in the production of blood. B12 deficiencies have been documented in people suffering from canker sores and studies have shown huge benefits for Vitamin B12 supplementation.

According to results published from a study in Spring 2009, conducted at the Ben-Gurion University of the Negev in Israel, B12 demonstrated huge benefits in treating canker sores. 74% of the treated group had total remission of canker sores. Average duration and severity were also decreased and after 6 months, had almost completely gone.

*References:
Volkov et al. Effectiveness of Vitamin B12 in Treating Recurrent Aphthous Stomatitis: A Randomized, Double-Blind, Placebo-Controlled Trial. The Journal of the American Board of Family Medicine, 2009; 22 (1): 9 DOI: 10.3122/jabfm.2009.01.080113
Sun A, Chen HM, Cheng SJ, Wang YP, Chang JY, Wu YC, Chiang CP. Significant association of deficiencies of hemoglobin, iron, vitamin B12, and folic acid and high homocysteine level with recurrent aphthous stomatitis. J Oral Pathol Med. 2015 Apr;44(4):300-5. doi: 10.1111/jop.12241. Epub 2014 Jul 22.
Lopez-Jornet P, Camacho-Alonso F, Martos N. Hematological study of patients with aphthous stomatitis. Int J Dermatol. 2014 Feb;53(2):159-63. doi: 10.1111/j.1365-4632.2012.05751.x. Epub 2013 Jul 24.
Kozlak ST, Walsh SJ, Lalla RV. Reduced dietary intake of vitamin B12 and folate in patients with recurrent aphthous stomatitis. J Oral Pathol Med. 2010 May;39(5):420-3. doi: 10.1111/j.1600-0714.2009.00867.x. Epub 2010 Feb 7.
Baccaglini L, Lalla RV, Bruce AJ, Sartori-Valinotti JC, Latortue MC, Carrozzo M, Rogers RS (2011). "Urban legends: recurrent aphthous stomatitis". Oral Diseases 17 (8): 755–770. doi:10.1111/j.1601-0825.2011.01840.x. PMC 3192917. PMID 21812866.

Propolis is a resinous mixture that honey bees collect from trees and plants. It has been used in traditional medicines for years and endorsed by institutes such as the National Institute of Health declaring it's "possibly effective" for treating cold sores, genital herpes, and post-surgery mouth pain. It has been shown to contain antibacterial and antifungal properties.

Researchers at Saudi Arabia's Salman bin AbdulAziz University found that treating cankers sores with honey reduced the pain and intensity of the sore and sped up healing times.

*References:
"Propolis: MedlinePlus Supplements". U.S. National Library of Medicine. January 19, 2012.
da Silva, F. B.; Almeida J. M.; Sousa S. M. (April–June 2004). "Natural medicaments in endodontics - a comparative study of the anti-inflammatory action". Braz Oral Res. 18 (2): 174–9. doi:10.1590/s1806-83242004000200015. PMID 15311323. Retrieved 2008-01-14.
Samet, N.; Laurent C.; Susarla S. M.; Samet-Rubinsteen N. (June 2007). "The effect of bee propolis on recurrent aphthous stomatitis: a pilot study". Clin Oral Investig. 11 (2): 143–7. doi:10.1007/s00784-006-0090-z. PMID 17285269.
Atanasovska Stojanovska A1, Popovska M, Muratovska I, Mitic K, Stefanovska E, Radojkova Nikolovska V. Therapeutic effect of proaftol in treatment of recurrent aphthous stomatitis.Prilozi. 2014;35(3):195-202.
Cherniack EP. Bugs as drugs, Part 1: Insects: the "new" alternative medicine for the 21st century?Altern Med Rev. 2010 Jul;15(2):124-35.
Martínez Silveira G, Gou Godoy A, Oña Torriente R, Palmer Ortiz MC, Falcón Cuéllar MA. Preliminary study of the effects of propolis in the treatment of chronic gingivitis and oral ulceration. Rev Cubana Estomatol. 1988 Sep-Dec;25(3):36-44.

Licorice is the root of Glycyrrhiza glabrahas. It has been used as a healing agent for more than 4,000 years and is known for its antiviral, antimicrobial and anti-inflammatory qualities. It is thought to soothe and coat injured tissues in the mouth, to help provide quick relief for canker sores. In addition, it numbs the injured tissue and covers the sore. It also acts as a pain reducer pain and helps speed up healing. Furthermore, it offers some extra benefits such as helping to prevent tooth decay and promote general oral hygiene care.

In one clinical trial, it was discovered that 80% of canker sore sufferers using an oral patch containing licorice root extract experienced significant pain reduction in just three days and managed to shrink the sore to one-tenth its original size after seven days. A further study found that 96% of canker sores treated with licorice root extract experienced significant healing within three days.

*References:
Borrelli F, Izzo AA. The plant kingdom as a source of anti-ulcer remedies. [Review]. Phytother Res. 2000;14(8):581-591.
Fiore C, Eisenhut M, Ragazzi E, Zanchin G, Armanini D. A history of the therapeutic use of liquorice in Europe. J Ethnopharmacol. 2005;99(3):317-24.
Messier C, Epifano F, Genovese S, Grenier D. Licorice and its potential beneficial effects in common oro-dental diseases. Oral Dis. 2012 Jan;18(1):32-9. doi: 10.1111/j.1601-0825.2011.01842.x. Epub 2011 Aug 18.
Mekseepralard C, Kamkaen N, Wilkinson JM. Phytother Res. Antimicrobial and antioxidant activities of traditional Thai herbal remedies for aphthous ulcers. 2010 Oct;24(10):1514-9. doi: 10.1002/ptr.3158.

Lysine is an amino acid which plays a major role in calcium absorption and the body's production of hormones, enzymes, and antibodies. Calcium deficiencies are thought to be present in canker sores sufferers. Therefore, lysine supplementation is thought to promote prevention of canker sores by assisting increased calcium intake.



*References:
Ogura M, Yamamoto T, Morita M, Watanabe T. A case-control study on food intake of patients with recurrent aphthous stomatitis. Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 2001 Jan;91(1):45-9.
Wright EF. Clinical effectiveness of lysine in treating recurrent aphthous ulcers and herpes labialis. Gen Dent. 1994 Jan-Feb;42(1):40-2; quiz 51-2.

Folic Acid is a B vitamin instrumental for many bodily functions. Nutritional folate deficiencies play a role in predisposing a person to canker sores. One study of people with canker sores found that over half were deficient in iron, folate, or vitamin BI2. When they supplemented their diets, almost all of them found that their canker sores disappeared. Supplementation is strongly recommended in the prevention of canker sores.

*References:
Sun A, Chen HM, Cheng SJ, Wang YP, Chang JY, Wu YC, Chiang CP. Significant association of deficiencies of hemoglobin, iron, vitamin B12, and folic acid and high homocysteine level with recurrent aphthous stomatitis. J Oral Pathol Med. 2015 Apr;44(4):300-5. doi: 10.1111/jop.12241. Epub 2014 Jul 22.
Lopez-Jornet P, Camacho-Alonso F, Martos N. Hematological study of patients with aphthous stomatitis. Int J Dermatol. 2014 Feb;53(2):159-63. doi: 10.1111/j.1365-4632.2012.05751.x. Epub 2013 Jul 24.
Kozlak ST, Walsh SJ, Lalla RV. Reduced dietary intake of vitamin B12 and folate in patients with recurrent aphthous stomatitis. J Oral Pathol Med. 2010 May;39(5):420-3. doi: 10.1111/j.1600-0714.2009.00867.x. Epub 2010 Feb 7.

Holy Basil leaves contain essential oils that produce eugenol, methyl eugenol and caryophyllenehas which have amazing purifying and cleansing properties. Scientific studies have established that compounds in basil oil have potent antioxidant, antiviral, and antimicrobial properties, making it an effective treatment for canker sores.



*References:
Bozin B, Mimica-Dukic N, Simin N, Anackov G (March 2006). "Characterization of the volatile composition of essential oils of some lamiaceae spices and the antimicrobial and antioxidant activities of the entire oils".J. Agric. Food Chem. 54 (5): 1822–8.doi:10.1021/jf051922u. PMID 16506839.
Chiang LC, Ng LT, Cheng PW, Chiang W, Lin CC (October 2005). "Antiviral activities of extracts and selected pure constituents of Ocimum basilicum". Clin. Exp. Pharmacol. Physiol. 32 (10): 811–6.doi:10.1111/j.1440-1681.2005.04270.x.PMID 16173941.
de Almeida I, Alviano DS, Vieira DP et al. (July 2007). "Antigiardial activity of Ocimum basilicum essential oil". Parasitol. Res. 101 (2): 443–52.doi:10.1007/s00436-007-0502-2. PMID 17342533.

Information on Canker Sores

Canker sores, also known as 'aphthous ulcers', are small, shallow ulcers that appear in the mouth and often make eating and talking very uncomfortable.

Statistics demonstrate that at least 20 percent of the population have canker sores at any one time. Other statistics indicate that women and teenagers are more prone to canker sores than men, and that canker sore suffering can be genetic in cause and susceptibility shared within family members.

Generally, canker sores are not a threat to your overall general health. However, the symptoms caused by canker sore attacks can interfere considerably with your day-to-day quality of life.

What is a Canker Sore?

Canker sores are known in the medical community as “aphthous ulcers" and they are classified in three forms:

Minor – Accounting for 80% of reported cases of canker sores in the general population. They are approximately 1-10mm in diameter and last anywhere from 7-10 days.

Major – These make up 10% of reported cases. These canker sores are larger than 10mm and anywhere between 10-30 days to heal and could result in scarring.

Herpetiform – These ulcers account for 7%-10% of canker sores. They can be located in the back of the mouth and although they are the smallest type of canker sores (pinpoint in size), they tend to occur in large simultaneous groups of sores. Women experience these type of sores more than men with the duration usually lasting between 7-14 days, however, they can persist for weeks. Even though the name suggests they may linked to herpes simplex 1 virus, they are classified as canker sores as opposed to cold sores.

Canker sores, on the whole, develop on 'movable' parts of the mouth – tongue, cheeks, lips, and at the base of the gums and they occur within the mouth, unlike cold sores. They start out as tiny, red “pimples" that usually burst within a day. Once ruptured, a thin white or yellow membrane will cover the sores. Generally, the vast majority of sores heal within two weeks without requiring treatment and without scarring.

Canker Sore Symptoms

Symptoms vary from person to person and individuals may have different symptoms during different attacks and differ in length and frequency.

They are small typically round or oval ulcers that cause a tingling or burning in the mouth. This sensation often occurs six to 24 hours before a canker sore appears. They are very painful.

They are usually not accompanied by other symptoms (like fever or swollen lymph nodes).

What are the Causes and Characteristics of Canker Sore?

The exact cause of canker sores is unknown. However, to date, researchers have been able to determine that canker sores do not appear to be caused by viruses or bacteria, although some studies demonstrate that that may develop as an allergic reaction to bacterium in the mouth.

They may also be the result of a weakened immune system where the body protects itself against and destroys normal mouth cells. Studies have found that vitamin B12, folic acid and iron deficiencies may be responsible for up to 20% of cases, and certain grains/cereals have been found in some people to cause a gastrointestinal reaction leading to canker sore development.

Other underlying health conditions that may affect canker sores include a weakened immune system; diet and nutritional problems, vitamin and mineral deficiencies; or gastrointestinal tract diseases such as celiac or Crohn's disease

Are Canker Sores and Cold Sores the Same Thing?

Cold sores and canker sores are very often confused between each other, they are different. Cold sores, often referred to as 'fever blisters' or 'herpes simplex type 1', are very painful, blisters, which can often be filled with fluid. Unlike canker sores, cold sores are caused by a virus and are very contagious. Also, while canker sores occur inside the mouth, cold sores generally appear outside the mouth appearing in places such as under the nose, around the lip area and/or under the chin. Cold sores can also 'cluster' with several cold sores occurring in the same location. Canker sores and cold sores require different treatments for successful elimination and prevention.

References:

1 - WebMD

2 - Wikipedia

3 - eMedicine Health

CankerClear™ - Frequently Asked Questions:

What makes CankerClear™ more effective than other canker sore treatments?
Most canker sore formulas combine a few key components with additional non-active ingredients, which can dilute the effectiveness of the product. This creates a cheaper solution and a less effective product. Others use inferior forms of critical ingredients, which just don't work as well. Some products neglect the research and include ingredients that are not even related to canker sores at all.

Only CankerClear™ uses a 100% natural formula that combines high quality ingredients in their most effective forms. This has enabled us to create an effective, multi-action formula that not only provides powerful, soothing relief to the painful symptoms and speeds up healing but also fights canker sores at the source to promote prevention. By combining these approaches, CankerClear™ has been able to create a superior remedy that works faster and is more effective than any other product on the market.

Can CankerClear™ be used to prevent symptoms from occurring?
Yes, many people use CankerClear™ as soon as they feel the tingling of canker sore to prevent the onslaught of symptoms from occurring. Since CankerClear™ is made of all natural ingredients, it is safe for long term use and are beneficial for prevention also.

How long should I use CankerClear™ ?
You can use CankerClear™ to get rid of symptoms, to prevent them from occurring, and to stop them from coming back. How long you should continue depends on how severe your symptoms are.

What makes up the ingredients of CankerClear™ ?
The ingredients in CankerClear™ can be found on our How It Works page. You can go there to read more about each of the quality natural herbal ingredients.

Why is CankerClear™ not available in stores?
We have chosen to make CankerClear™ available exclusively online, so that we are able to reach more people and maintain control of distribution and customer service. We want to be hands on with our customers if there's a problem; we lose that personal touch when the product is sold in stores.

Can I see the label of CankerClear™
Of course! Please click here to see our label.

Can I use CankerClear™ with my prescription medications?
CankerClear™ has been formulated using only the purest natural ingredients. For the most part, there is no interference with most medications. But if you have any concerns, we always recommend you consult with your doctor.

If it does not work for me and I want to return it, what do I do?
Not a problem - there is a 60 day money back guarantee. We ask that you call customer service to get your return authorization number. If you do decide to return the jars, you must return all of the jars, so do not throw any of them away. Please do not ship products to us after the 60 day period has expired. If you send only a portion of the jars back, you will receive a partial refund.

Questions about Shipping CankerClear™ :

How soon will my order arrive?
If you choose regular shipping, CankerClear™ is shipped by US Postal Service First Class Mail. If you place your order before 10:00am EST, it will be shipped out on the day it is ordered. If you place your order after 10:00am EST, it will be sent out the next morning. Your order should arrive within 3 to 5 business days within the USA. All orders received after 10:00am on Friday or on the weekend will be shipped out promptly Monday morning.

We also offer FedEx 2 day delivery, as well as next day shipping. FedEx shipments will be sent out the same day, as long as the order is received by 10:00am EST. You can learn more about shipping options on the checkout page.

What kind of package will it arrive in?
We always ship discreetly to protect the privacy of our customer. CankerClear™ is shipped in plain packaging with no external information that identifies the product purchased.

How secure is it to order CankerClear™ online?
Very secure. We use the strongest data encryption Secure Sockets Layer (SSL) technology available. SSL technology is the industry standard for encryption, and ensures a secure transaction environment for commerce on the internet.

Do you ship to Canada?
Yes, we have many customers in Canada; it just takes longer to get there, about 1 to 2 weeks for regular mail. If you order it using the FedEx amount, it will take 4 to 6 days.

Do you ship internationally?
Yes, we can ship to any country. You can learn more about shipping options on the checkout page.